They may also have you see your dentist. Whats the Connection Between Estrogen and Osteoporosis? How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, https://www.ada.org/en/member-center/oral-health-topics/osteoporosis-medications, https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/125320s210lbl.pdf, New clues to slow aging? Over time, Prolia can reduce bone loss and make your bones stronger. In this article well discuss the uses, side effects, safety precautions, and other important information about Prolia. Bone density decreases with time, and some people have a risk of developing weak or brittle bones. If youre concerned about hair loss with Prolia, talk with your doctor. Call your doctor for medical advice about side effects. You might be interested in seeing how Prolia and the drug Boniva compare. Prolia may cause serious side effects. Your doctor may suggest limiting foods that are high in trans fats, such as fried foods. Call your doctor or go to your nearest emergency room right away if you have any symptoms of a serious allergic reaction, including low blood pressure (hypotension); trouble breathing; throat tightness; swelling of your face, lips, or tongue; rash; itching; or hives. Denosumab is contraindicated in women with hypocalcaemia. Other drugs may interact with denosumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Prolia contains the active ingredient denosumab. Research has shown people who take Prolia are at an increased risk of serious infections leading to hospitalizations, including endocarditis and serious infections of the skin, abdominal, urinary tract, and ear. Xgeva is another brand of denosumab used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone. Prolia is a medicine that may affect the ability of your body to fight infections. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Prolia is a prescription medicine used to treat osteoporosis in men and women who will be taking corticosteroid medicines (such as prednisone) for at least six months and are at high risk for fracture. Prolia is a RANKL inhibitor. Medically reviewed by Sanjai Sinha, MD. The use of the eHealthMe site and its content is at your own risk. Inflammation of the inner lining of the heart (endocarditis) due to an infection may also happen more often in people who take Prolia. Increased risk of broken bones, including broken bones in the spine, after stopping, skipping or delaying Prolia. Below are answers to some commonly asked questions about Prolia. But doing so can cause more bone breakdown and increase your risk for bone fractures. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Take only the amount of calcium and vitamin D that your doctor has prescribed. Different individuals may respond to medication in different ways. You may wonder how Prolia compares to the medication Zometa. Brush and floss your teeth regularly. Common interactions include nausea among females and fatigue among males. For Prolia, talk to your pediatrician regarding the use of this medicine in children. (Biosimilars are like generic drugs. It strengthens your bones by stopping certain bone cells called osteoclasts from breaking down your bones. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Prolia. Prolia is a monoclonal antibody. * Sex and gender exist on spectrums. If you develop high cholesterol with Prolia, your doctor can guide you on which treatment options are right for your condition. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs.) What should I know about Prolia vs. Fosamax? Its a, Forteos active ingredient is teriparatide. Prolia is a prescriptionmedicine used to treat bone loss in women who are at high risk for fracture receiving certain treatments for breast cancer that has not spread to other parts of the body. They also include any added costs of the drug being given by a healthcare professional. Hair loss with Prolia was reported after the drugs initial studies were done and it was approved for use. They can treat the infection as needed. But weight gain may occur with other medications you take or other health conditions you have. 1 shot every 6 months could mean fewer doses. Others may continue for as long as you take the drug, but they can be easily managed. In rare cases, your doctor may have you self-inject Prolia at home. Some people have developed unusual fractures in their thigh bone. With peripheral edema, fluid builds up in your body and causes swelling in your arms and lower legs. Talk with your doctor about the risks of using this drug during pregnancy. If your pain doesnt ease with OTC options, your doctor may suggest prescription pain medication. Common Talk with your doctor before starting Prolia treatment. Prolia can also cause bones to not form correctly and reduced growth in a fetus. And if you have osteoporosis, falling could increase your risk of fractures. Theyll do this with certain tests, such as a bone scan or ultrasound. Continue reading, Yes, Prolia does appear to weaken your immune system. You should always consult your doctor or another healthcare professional before taking any medication. But certain choices and habits accelerate the process. Studies have found that Prolia is generally safe and effective to treat osteoporosis and certain types of bone loss. You should also take calcium and vitamin D supplements while being Additionally, in Prolia-treated men with nonmetastatic prostate cancer receiving ADT, a greater incidence of cataracts was observed. 2023 Healthline Media LLC. Motion sickness, nausea, and vomiting can occur as a part of vertigo. Learn about the highest quality calcium supplements here. So be sure to talk with your doctor about any past or upcoming surgery before starting treatment with the drug. * Sex and gender exist on spectrums. Prolia is usually given once every 6 months. No one in clinical trials of Prolia had to stop taking the drug due to dizziness. Learn more about the FRAX score and the treatment options for, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. (A low blood calcium level is a possible side effect of Prolia.). Dosage of drugs is not considered in the study. Adults over age 50 should not exceed 2,000 mg total per day. Vertigo (dizziness) was reported in some people who received Prolia for osteoporosis, but this was a less common side effect. If they find any cavities or infection, theyll typically delay having you receive Prolia until your dental problems are treated. What are some frequently asked questions about Prolia? If you notice any tooth or jaw pain, or sensitivity while using Prolia, talk with your doctor or dentist right away. Tell your doctor if youd like to know more about these drugs. Your doctor can discuss with you how to manage side effects and whether youll need to stop taking Prolia due to side effects. Talk with your doctor if youd like to know about taking generic denosumab. You may need to have a negative pregnancy test before starting this treatment. People need calcium for bone health and other functions. Low blood calcium level. If you keep this medicine at home, store it in the original carton in a refrigerator. Your doctor will recommend the dosage of Prolia thats right for you. Do not take this medicine with any of the following medications: This medicine may also interact with the following medications: This list may not describe all possible interactions. Sciatica was a less common side effect in females* who received Prolia for osteoporosis after menopause. If you have osteoporosis or bone loss, your doctor may discuss Prolia as a treatment option. Your doctor can give you more information about the risks and benefits and how Reclast compares with Prolia. It is not known if the use of Prolia over a long period of time may cause slow healing of broken bones. Prolia contains the same medicine as XGEVA (denosumab). Our phase IV clinical studies alone cannot establish cause-effect relationship. If youre using Prolia and feel fatigued despite getting enough sleep, talk with your doctor. Like most drugs, Prolia may cause mild or serious side effects. But its not clear how often this side effect occurred in clinical trials. Prolia also carries a warning about hypocalcemia, which is a low level of You are encouraged to report negative side effects of prescription drugs to the FDA. If you have questions about treatment options for osteopenia or arthritis, talk with your doctor. The study uses data from the FDA. This includes proper brushing, flossing, mouthwash use, and regular professional dental cleanings. (With off-label use, a drug is used to treat conditions other than those its been approved to treat.) For more information about how Prolia and Zometa compare with each other, see this article. Its important to tell your doctor if you have serious or ongoing side effects. low calcium level--muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes). To help prevent low calcium, your healthcare provider may also A biologic drug is made from parts of living organisms. It is not safe to receive Prolia during pregnancy. These include osteonecrosis of the jawbone. Every 6 months youll get another dose of Prolia. Boniva contains the active drug ibandronate, but Prolia contains the active drug denosumab. Its also recommended that you use birth control while taking Prolia and for 5 months or more after your last dose. For information about the difference between sex and gender, see this article. Your risk for having more than 1 broken bone in your spine is increased if you have already had a broken bone in your spine. For example, an over-the-counter pain reliever can often ease mild pain such as joint or muscle pain, or headache. Costs of prescription drugs can vary depending on many factors. Youll likely have questions about your condition and treatment choices. This increases your risk for bone fractures. Xgeva is another brand of denosumab that treats high calcium levels caused by cancer and prevents bone breaks. Our website services, content, and products are for informational purposes only. Call your doctor for medical advice about side effects. Other side effects may continue for as long as you receive the medication, but they can often be relieved with other treatments. WebStudies have shown that people who live more sedentary lifestyles are at an increased risk of developing osteoporosis. These problems may include: Your risk for mouth-related side effects may be higher if you have problems with your teeth. Mild side effects can occur with Prolia use. It may also be higher if you have dental work done while youre taking Prolia. Prescribing Information and Learn how to increase or maintain bone density here. It is advisable to take 2 capsules in the morning with food and 1 in the evening also with food. And theyll recommend if its the best option for your condition. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. Be sure to talk with your doctor about which medication is right for you. Some people may have dental or jaw-related issues with Prolia use. In addition, Prolia may also be used off-label for other conditions that cause bone loss or loss of bone mineral density. They may help you identify other possible causes or suggest ways to help manage hair loss. Because Prolia can also cause low blood calcium, your risk may increase if you receive Prolia. What should I know about Prolia vs. Reclast? Prolia is also available in a biosimilar form. Calcium supplements may help support bone and teeth health. What should I know about Prolia vs. Boniva? Osteoporosis medications and medication-related osteonecrosis of the jaw. There is a potential for serious side effects to an unborn child. But it can increase your risk of serious health problems, such as heart attack. Do not share this medicine with others. Weakness and tingling can also occur. What Health Changes Should You Expect Postmenopause? Learn more about some of the side effects Prolia may cause. Heres some information on pregnancy, breastfeeding, and Prolia use. eHealthMe is studying from 138,307 Prolia users for its effectiveness, alternative drugs and more. For example, in the studies, people taking Prolia for up to 8 years didnt have significant side effects compared with people taking a placebo. Some people may have an allergic reaction to Prolia. The most common medications prescribed to lower cholesterol are statins. Also describe any vitamins, herbs, or supplements you use. After your treatment with Prolia is stopped, or if you skip or delay taking a dose, your risk for breaking bones, including bones in your spine, is increased. alan rickman net worth 2021, jenison high school homecoming 2021,
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